| Autor: |
Petrichenko, V. M., Sukhinina, T. V., Shramm, N. I., Babiyan, L. K., Yushkov, V. V. |
| Předmět: |
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| Zdroj: |
Pharmaceutical Chemistry Journal; Mar2005, Vol. 39 Issue 3, p145-148, 4p |
| Abstrakt: |
The content of moisture, ash, extractive substances, and impurities in dry extract from eyebright ( Euphrasia brevipila) grass has been studied. The content of the main biologically active components, flavonoids and iridoids, has been estimated at 3.56 – 6.81% and 0.44 – 0.69%, respectively. The optimum method of extraction for a material crushed to particle size within 0.25 – 2.0 mm is repercolation using 40% ethanol, with a phase contact time of 8 – 16 h at every stage. The yield of dry extract (containing 19.84% of flavonoids and 2.27% of iridoids) was 14.75%. This extract possessed antiinflammatory activity in a dose range from 10 to 300 mg/kg; the acute toxicity is 4470 mg/kg. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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