| Autor: |
Kim, Jowon L., Chercover, David, Masoudi, Hamid, Foltz, Lynda |
| Zdroj: |
BMJ Case Reports; Nov2024, Vol. 17 Issue 11, p1-6, 6p |
| Abstrakt: |
Bupropion is not a well established cause of medication-induced pancytopenia. In this report, we discuss a case of agranulocytosis, normocytic anemia and severe thrombocytopenia, with concurrent drug-induced rash within 3 weeks of bupropion initiation. Bone marrow biopsy demonstrated hypocellularity <10% without dysplastic features or increase in blast cells. Other causes of cytopenias, including infections, nutritional deficiencies, autoimmune disorders, liver/renal disease, thrombotic microangiopathy, primary bone marrow disorders and secondary marrow infiltrative diseases were ruled out. Pancytopenia resolved after 1 week of bupropion discontinuation and supportive care. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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