| Autor: |
Dhiman, Surekha, Gharu, Yuvraj, Gupt, Anju Madan, Sarkar, Malay, Rajta, Puja Negi |
| Předmět: |
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| Zdroj: |
European Journal of Cardiovascular Medicine; 2024, Vol. 14 Issue 3, p497-502, 6p |
| Abstrakt: |
Background: COPD primarily affects the lungs and is characterized by weight loss and decline in exercise tolerance. We aimed to determine the nutritional status evaluated by BMI (Body Mass Index) and FFMI (Fat Free Mass Index) according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) levels in stable subjects with COPD and the association between FFMIand exercise capacity with COPD severity. Method: Forty-eight patients of clinically stable COPD attending the outpatient department of pulmonary medicine, were recruited for the study. They were classified into the COPD GOLD stages and were evaluated for BMI, BFMI (Body Fat Mass Index), FFMI (measured by bioelectrical impedance analysis), airway obstruction and hyperinflation (FEV1, FEV1/FVC) and exercise capacity (6-min walk distance). Result: The mean values of FFMI (p=0.035) and BMI (p=0.008) were significantly lower in severe COPD cases (GOLD stage 3&4). The independent predictors for low fat free mass index with statistically significant difference were female gender (beta= -0.216 and p=0.034) and low BMI (beta=-0.678 and p=<0.001). Six-minute distance covered was less (p=0.016) in severe COPD cases (GOLD stage 3&4) and with low FFMI patients. Conclusion: FFMI presented significant correlations with COPD severity and so may serve as useful predictor of COPD severity. Abnormal body composition is an important non-pulmonary impairment that modulates the risk of functional limitation in COPD. Body composition abnormalities may represent an important area for screening and preventive intervention in COPD and can be used for the long term health benefits in COPD patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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