| Abstrakt: |
Researchers at the Max-Planck-Institute for Dynamics for Complex Technical Systems in Magdeburg, Germany, conducted a study on the production of recombinant vesicular stomatitis virus-based vectors using tangential flow depth filtration systems. The study focused on continuous virus harvesting and clarification using suspension cells and different filtration methods. While the cell-specific virus yield decreased compared to a batch process, an increased space-time yield was achieved. This research provides valuable insights into the production of vector-based vaccines and virotherapeutics. [Extracted from the article] |
