New Personalized Medicine Study Findings Recently Were Reported by Researchers at Medical College of Wisconsin (Cancer-associated Polybromo-1 Bromodomain 4 Missense Variants Variably Impact Bromodomain Ligand Binding and Cell Growth Suppression).

Předmět:	BIOCHEMISTRY MOLECULAR biology MISSENSE mutation CHEMICAL biology POST-translational modification
Zdroj:	Cancer Weekly; 12/3/2024, p1030-1030, 1p
Abstrakt:	Researchers at the Medical College of Wisconsin have conducted a study on the impact of missense variants in the fourth bromodomain of the PBRM1 protein on cancer cell growth suppression. The study focused on identifying the unique effects of these variants on protein structure and function, providing insights for personalized medicine approaches in cancer treatment. Funded by various organizations including the National Institutes of Health, the research sheds light on potential correlations between specific PBRM1 missense variants and alterations in protein function. The findings were published in the Journal of Biological Chemistry. [Extracted from the article]
Databáze:	Complementary Index
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