| Abstrakt: |
A recent study conducted at the Neuroscience Institute Cavalieri Ottolenghi in Turin, Italy, focused on modeling primary microcephaly using human brain organoids to understand the role of Cit kinase activity in brain development. The research highlighted the importance of CIT catalytic and scaffolding functions in neural progenitor cell cytokinesis for human corticogenesis. The study emphasized the utility of human forebrain organoid models in elucidating human microcephaly and species-specific differences in corticogenesis. Funding for the research was provided by various organizations, including the NIH and Italian Ministry of University and Research. [Extracted from the article] |
