Evolution of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits Over a Decade.

Autor:	Bhowmik, Dipankar, Singh, Geetika, Mandal, Shilpa, Dhawan, Rishi, Balakrishnan, Muthukumar, Duggal, Rajan
Předmět:	THERAPEUTIC use of immunoglobulins THERAPEUTIC use of monoclonal antibodies CONSERVATIVE treatment PROTEINURIA BIOPSY COMBINATION drug therapy CREATININE TREATMENT effectiveness DIURETICS FLUORESCENT antibody technique PREDNISOLONE GLOMERULONEPHRITIS NEPHROTIC syndrome ANGIOTENSIN receptors BORTEZOMIB METHYLPREDNISOLONE ALBUMINS CYCLOPHOSPHAMIDE DEXAMETHASONE
Zdroj:	Indian Journal of Nephrology; Sep/Oct2024, Vol. 34 Issue 5, p514-2, 2p
Abstrakt:	Infections remain an important cause of morbidity in kidney transplant recipients, particularly in the early post-transplant period. This window coincides with an increased risk of acute rejections. Prompt identification of the cause of graft dysfunction is paramount to ensure good outcomes. This case report presents a 32-year-old male undergoing his second living-related kidney transplantation, complicated by herpes simplex virus-2 (HSV-2) nephritis. Despite favorable initial graft function, he developed odynophagia postoperatively, leading to the diagnosis of HSV-related esophageal ulcers. Subsequent acute graft dysfunction prompted biopsy, revealing HSV-2 related acute tubular injury. Prompt initiation of intravenous acyclovir resulted in graft recovery. This case underscores the importance of considering uncommon viral etiologies in post-transplant complications and highlights the role of timely diagnosis and treatment in preserving graft function. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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