| Autor: |
Jihye Lim, Hyundam Gu, Dong Jin Chung, Kwang Yeol Paik, Seung Kew Yoon, Yeonjoo Seo, Moonjin Kim, Se Hyun Cho |
| Zdroj: |
Gut & Liver; 2024 Supplement, Vol. 18, p122-122, 1/4p |
| Abstrakt: |
Background/Aims Microwave ablation (MWA) represents an emerging ablative therapy that surpasses previous methods by achieving higher temperatures and creating larger ablation zones within shorter time periods. This study aimed to compare therapeutic outcomes of MWA and liver resection in real-world clinical practice. Methods This study enrolled 178 patients with 259 nodules who underwent either MWA or liver resection between January 2015 and July 2023. Local tumor progression (LTP)-free survival, overall progression (OP)-free survival, and overall survival (OS) were assessed based on treatment modality of the index nodule. Results Of a total of 178 patients, 134 patients with 214 nodules received MWA and 44 patients with 45 nodules underwent liver resection. The median follow-up period was 2.0±1.5 years. Annual incidence of LTP was 3.7% for MWA and 1.4% for liver resection. Treatment modality showed no significant impact on LTP-free survival. For nodules larger than 3 cm, LTP-free survival was not affected by treatment modality. Similarly, OP-free survival (adjusted hazard ratio [HR]: 0.95, p=0.864) and OS (adjusted HR: 0.79, p=0.707) were not influenced by the choice of treatment modality. Conclusion In conclusion, MWA and liver resection demonstrated comparable treatment outcomes in terms of local tumor control, overall recurrence, and survival. Establishment of better-fit indications for each procedure necessitates specifically designed studies. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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