| Autor: |
Maity, Dhananjoy, Maity, Ramkrishna, Jana, Manoranjan, Hajra, Saumen |
| Předmět: |
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| Zdroj: |
Synlett; Dec2024, Vol. 35 Issue 20, p2542-2546, 5p |
| Abstrakt: |
A concise and scalable asymmetric synthesis of (+)-8-epigrosheimin is reported in nine steps using only three column chromatographic purifications with an overall yield 47.0% from (R)-(–)-carvone. Two synthetic routes are evaluated by catalyst-free tandem allylboration–lactonization of two carvone-derived aldehydes and subsequent ene cyclization, where strategy via Lee–Lay aldehyde is found to be more effective for 8-epigrosheimin. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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