Nickel-Catalyzed O -Methylation of Cinnamic Acid Using DMSO as Methyl Surrogate.

Autor: Talukdar, Hrishikesh, Phukan, Prodeep
Předmět:
Zdroj: Synlett; Dec2024, Vol. 35 Issue 20, p2515-2519, 5p
Abstrakt: A new method for the O -methylation of cinnamic acid employing DMSO as the methylating agent has been devised, employing a Ni-DMAP complex as catalyst along with Ag2 O and dimethylamine as additives. This protocol demonstrates broad substrate compatibility and good tolerance towards various functional groups. The key advantages of this approach include the utilization of cost-effective catalysts, moderate to high yield of the products, and short reaction time. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index