Autonomic function and change in functional capacity in older adults: a longitudinal investigation.

Autor: Wu, I-Chien, Lu, Yung-Yi, Tseng, Wei-Ting, Chen, Pei-Fen
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Zdroj: Scientific Reports; 11/24/2024, Vol. 14 Issue 1, p1-9, 9p
Abstrakt: Functional capacity is an important objective health metric, and relies on the maintenance of physiological homeostasis. Autonomic nervous system is known to coordinates the maintenance of multi-organ homeostasis. The objective of this study was to examine the association of autonomic nervous system function with functional capacity in adults aged 55 years and older. A cohort of 542 adults (mean age of 70.1 years) received repeated measurements of heart rate variability, an autonomic nervous system function marker, and chair rise time, a functional capacity measure. Linear mixed models analysis showed that 1 SD lower powers in low-frequency range at baseline was associated with a 0.11 (95% CI 0.01–0.21) s/year faster increase in chair rise time during the follow-up, whereas 1 SD increase in powers in high-frequency range and 1 SD decrease in the ratio of powers in low-frequency range to powers in high-frequency range during the follow-up were associated with a 0.22 (95% CI 0.06–0.39) s and 0.17 (95% CI 0.01–0.33) s increase in chair rise time. In conclusion, autonomic nervous system function and its changes were longitudinally associated with changes in functional capacity in older adults. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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