| Autor: |
نگین حسینی روزبهانی, خدایار قربان, مجید زمانی, محمد حسن کاظمی گلوگاهی, مریم دادمنش, محمد غلامی |
| Předmět: |
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| Zdroj: |
Paramedical Sciences & Military Health; 2024, Vol. 19 Issue 1, p39-50, 12p |
| Abstrakt: |
Introduction: There are very limited studies about the relationship between the presence of autoimmune disease and the patients' outcome with Covid-19. Therefore, this study aimed to investigate the prevalence of various autoimmune disorders in patients with Covid-19 and its relationship with the prognosis of this group of patients. Materials and Methods: In this retrospective cohort study, the sample size included 264 patients with autoimmune disease who were hospitalized in Tehran Army hospitals due to Covid-19 disease. Moreover, 283 patients with non-autoimmune disease were considered as the control group. Patients' information was achieved using their hospital records. Demographic and information about disease history and their ultimate outcome were recorded. Finally, descriptive statistics indicators of mean and standard deviation were used to describe data. Furthermore, data were analyzed using SPSS software version 24 through independent t-Test and K2. Result: In the group with autoimmune diseases, the mean age of patients was 55.32 ±7.63 years old. The most common disease was rheumatoid arthritis (21.2%) followed by psoriasis (12.9%). Mortality rates were significantly higher in the group with autoimmune disease compared with patients in the control group (18.9% vs. 11.3%, p = 0.012). The frequency of admission in the intensive care unit and intubation in the group with autoimmune diseases was significantly higher than control group (p <0.0001). Based on logistic regression, the presence of autoimmune disease increases the chance of death (Odds Ratio = 1.484) and it increases the chance of admission to the intensive care unit lonely (Odds Ratio = 1.487) (P <0.05). Conclusion: The results indicate that, based on modeling, autoimmune diseases significantly increase the chance of death and they also increase the chance of admission to the intensive care unit compared with healthy people. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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