Abstrakt: |
Researchers from Ravenshaw University in Odisha, India, have developed a new method for synthesizing spiro indanone fused pyrano[2,3-c]chromene derivatives with antibacterial properties. The study utilized oxa-Diels-Alder reaction and computational investigations to validate the reaction pathway. Compound 20e showed promising antibacterial activity against Escherichia coli and Staphylococcus aureus, making it a potential candidate for future antibacterial agents. The research was supported by various organizations and has been peer-reviewed, indicating its credibility and significance in the field of drug development. [Extracted from the article] |