Abstrakt: |
Researchers at the Institute for Regenerative Medicine have conducted a study on the potential use of extracellular vesicles (EVs) derived from human-induced pluripotent stem cell-derived neural stem cells to alleviate proinflammatory cascades in Alzheimer's disease. The study involved administering these EVs to mice with AD, resulting in reduced activation of microglia and astrocytes, as well as improvements in cognitive and mood function. This research suggests that early intervention with these EVs could help maintain better brain function in AD patients by reducing neuroinflammatory signaling cascades, amyloid-beta plaque load, and p-tau levels. [Extracted from the article] |