Research Findings from Zibo Municipal Hospital Update Understanding of Squamous Cell Carcinoma (The radiosensitivity of niraparib tosylate to esophageal squamous cell carcinoma is stronger under hypoxia and higher-pressure conditions).

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Zdroj: Cancer Weekly; 11/26/2024, p870-870, 1p
Abstrakt: A recent study conducted at Zibo Municipal Hospital focused on the radiosensitivity of niraparib tosylate in treating esophageal squamous cell carcinoma (ESCC). The research found that niraparib tosylate, a poly ADP-ribose polymerase (PARP) inhibitor, enhanced the radiosensitivity of ESCC cells, leading to increased apoptosis and G2/M cycle arrest. The study also showed that the combination therapy of niraparib tosylate and radiotherapy was more effective under hypoxic and high-pressure conditions. These findings suggest a potential clinical application of niraparib tosylate in cancer therapy. [Extracted from the article]
Databáze: Complementary Index