| Autor: |
Kmetski, Ts., Velcheva, I., Antonova, N., Tsonevska, G., Stambolieva, K., Alexandrova, A., Bechev, B. |
| Předmět: |
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| Zdroj: |
Neurosonology & Cerebral Hemodynamics; 2024, Vol. 20 Issue 2, p222-223, 2p |
| Abstrakt: |
Objective: The carotid stiffness is an important factor in the pathogenesis of cerebrovascular small vessel disease. Our study aimed to evaluate the relation of the local arterial stiffness of the common carotid artery CCA) to the hemodynamic forces in patients with cerebral lacunar infarctions (LI). Methods: The study includes 22 patients with chronic LI and 15 age-matched controls. An ultrasound examination of the CCA intima-media thickness (IMT), the parameters of local CCA stiffness: distensibility (DC) and compliance coefficients (CC), α and β stiffness indices and pulse wave velocity (PWV) were performed. The local hemodynamic forces were calculated: circumferential wall tension (CWT) and wall shear stress (WSS). Results: Higher values of IMT, a significant decrease of DC and CC and an increase of α and β stiffness indices and PWV in the LI patients compared to the controls were obtained. A parallel significant increase in CWT and a decrease in WSS were found. In the LI patients, the increased stiffness indices were associated with an increase in age and cholesterol in the left CCA. In the controls, the IMT correlated significantly with the hemodynamic factors in both CCAs, while the stiffness indices correlated with the hemodynamic forces in the left CCA. Conclusion: The results of the present study demonstrate different associations of the local carotid stiffness indices with the hemodynamic forces in patients with LI and controls. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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