Demographic and Clinical Characteristics of Pre-Malignant Oral Lesions and their Related Factors in an Iranian Population: A Registry-Based Study.
| Autor: | Rahmani, Somayeh, Shirmardi, Maryam Sadat, Baharvand, Maryam, Mortazavi, Hamed |
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| Předmět: |
RISK assessment
MOUTH tumors COMPUTER software T-test (Statistics) PRECANCEROUS conditions SCIENTIFIC observation FISHER exact test SMOKING SEX distribution ORAL mucosa SYMPTOMS REPORTING of diseases CHI-squared test ORAL leukoplakia DESCRIPTIVE statistics FAMILY history (Medicine) AGE distribution BLOOD groups BURNING mouth syndrome IRANIANS SOCIODEMOGRAPHIC factors DENTAL schools DATA analysis software ORAL lichen planus COMPARATIVE studies DISEASE risk factors |
| Zdroj: | Journal of Iranian Medical Council (JIMC); Autumn2024, Vol. 7 Issue 4, p746-756, 11p |
| Abstrakt: | Background: Oral Potentially Malignant Disorders (OPMDs) can lead to Oral Squamous Cell Carcinoma (OSCC). The sixth most common cancer in the world is OSCC. This study aimed to describe the demographical and clinical characteristics of OPMD patients and their risk factors registered at the Oral Medicine Department of Shahid Beheshti Dental School in 2019-2021. Methods: The observational-analytical study was conducted using the dental records of 96 consecutive patients using a web-based registration software (OPMDs registry). Information including demographics and clinical features, the type of OPMD, and risk factors were extracted. Data were analyzed using the Chi-square test, T-test, and Fisher’s exact test with SPSS version 21. Results: In this study, 96 patients (average age: 52.41±14.87) including 52 women and 44 men, participated. The most common OPMDs comprised 69 Oral Lichen Planus (OLP) and 15 leukoplakia. The most common location of lesions was the buccal mucosa (74%) with erosions and plaques being the most common morphology types. Most patients with leukoplakia were male, however, majority of the patients with OLP were female (p=0.001). In patients with leukoplakia, 66.5% were smokers; hence, a significant relationship between smoking and OPMD was observed (p=0.001). Patients with OLP commonly presented with burning symptoms, while patients with leukoplakia were mostly asymptomatic (p=0.004). Conclusion: A significant relationship was observed between gender, clinical symptoms, location of lesions, morphology, and type of OPMDs. Most patients with OPMDs were women with OLP in their buccal mucosa, suffering from burning sensation. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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