Size dependent properties of Gd3+-free versus Gd3+-doped carbon dots for bioimaging application.

Autor:	Zhylkybayeva, Nazym, Paliienko, Konstantin, Topchylo, Anna, Zaderko, Alexander, Géloën, Alain, Borisova, Tatiana, Grishchenko, Liudmyla, Mariychuk, Ruslan, Skryshevsky, Valeriy, Mussabek, Gauhar, Lysenko, Vladimir
Předmět:	MAGNETIC resonance imaging OPTICAL properties INFRARED spectroscopy CELL imaging LIGHT scattering
Zdroj:	Scientific Reports; 11/16/2024, Vol. 14 Issue 1, p1-13, 13p
Abstrakt:	Gd3+- free carbon dots (CDs) were synthesized by one-step solvothermal method using urea, citric acid and 3-(trifluoromethyl)aniline as precursors. Additionally, Gd3+-doped CDs were prepared by incorporating gadolinium chloride (Gd3+ ions) into the synthesis. Size selection of the purified CDs was achieved through filter membranes ranging from 3 kDa to 100 kDa. The chemical composition and optical properties of the obtained samples were characterized by Energy dispersive X-ray (EDX), Fourier-transform infrared spectroscopy (FTIR), Dynamic Light Scattering (DLS), proton relaxation time measurements, Ultraviolet–visible (UV-vis) and fluorescence spectroscopies. A comparative analysis revealed a strong size-dependent behavior in the optical properties of both Gd3+-doped and Gd3+-free CDs. Furthermore, in vitro tests confirmed the non-cytotoxicity of Gd3+-doped CDs, indicating their potential applicability in biomedicine for magnetic resonance imaging (MRI) and red fluorescence-based cell and tissue imaging. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.