Combined detection of Chlamydia trachomatis-specific antibodies against the 10 and 60-kDa heat shock proteins as a diagnostic tool for tubal factor infertility: Results from a case-control study in Cameroon

Autor: Dadamessi, Innocenti, Eb, François, Betsou, Fotini
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Zdroj: FEMS Immunology & Medical Microbiology; Jul2005, Vol. 45 Issue 1, p31-35, 5p
Abstrakt: Abstract: A case-control study was conducted to determine the diagnostic value of Chlamydia trachomatis-associated anti-Chsp10 and/or anti-Chsp60 antibodies in the detection of secondary infertility. There were significant associations between C. trachomatis infection and infertility (p <0.01), and between C. trachomatis-specific anti-Chsp10 or anti-Chsp60 antibodies and secondary infertility (p <0.001). A significant correlation was found between anti-Chsp10 and anti-Chsp60 titers (p <0.01). The detection of either C. trachomatis-associated anti-Chsp10 or anti-Chsp60 antibodies cumulatively allowed specific diagnosis of secondary infertility (57.4% sensitivity, 75.5% specificity). [Copyright &y& Elsevier]
Databáze: Complementary Index