| Autor: |
He, Lanfeng, Wang, Enhua, Zheng, Shuang, Ban, Yingguo, Hou, Kaiping, Yang, Lishou, Yang, Xiaosheng |
| Předmět: |
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| Zdroj: |
ChemistrySelect; 11/15/2024, Vol. 9 Issue 43, p1-4, 4p |
| Abstrakt: |
A diethyl phosphate (DEP)‐catalyzed one‐pot synthesis of 2,3‐dihydroquinolin‐4(1H)‐ones in DMF was achieved. Control experiments led to a plausible mechanism involving an intermolecular aldol condensation of 2‐aminoacetophenone and aldehyde, followed by a hydrogen bond‐driven cyclization. In this process, a series of 2,3‐dihydroquinolin‐4(1H)‐ones were obtained in good yields (48–84%). This strategy features transition metal‐free and short reaction times. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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