| Abstrakt: |
A recent study conducted at Griffith University in Nathan, Australia, has identified N,N-dialkyl-5-alkylsulfonyl-1,3,4-oxadiazol-2-amines as a new class of slow-acting antiplasmodial agents against Plasmodium falciparum malaria parasites. The research aimed to find new preventative agents that act differently from current front-line treatment drugs to aid in malaria eradication. While these compounds show promise, further development for malaria chemoprophylaxis will require improvements in their pharmacokinetic profile. This study was supported by Monash University Technology Research Platform network and Therapeutic Innovation Australia through the Australian Government National Collaborative Research Infrastructure Strategy program. [Extracted from the article] |
