Shiraz University of Medical Sciences Researcher Targets Gene Therapy (Unlocking Therapeutic Potential: Enhanced shRNA Delivery with Tat Peptide in the Human Respiratory Syncytial Virus Treatment).

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Zdroj: Gene Therapy Weekly; 11/19/2024, p2393-2393, 1p
Abstrakt: A recent study conducted by researchers at Shiraz University of Medical Sciences in Iran focused on developing short hairpin RNA (shRNA) molecules to target specific regions of the human respiratory syncytial virus (HRSV) M and F genes. The study aimed to evaluate the therapeutic potential of these shRNAs and assess the effectiveness of Tat peptide-mediated delivery in enhancing their functionality. Results showed that Tat peptide-mediated delivery of shRNA plasmids significantly suppressed the expression of HRSV genes, indicating a promising gene therapy strategy for HRSV treatment. Further research is needed to evaluate the potential of this approach in clinical settings. [Extracted from the article]
Databáze: Complementary Index