| Abstrakt: |
The University of Udine conducted research on the role of sex in liver tumor occurrence and clinical outcomes, highlighting the differences in manifestations, pathophysiology, and prevalence of liver diseases between men and women. The study emphasized the impact of sex hormones on liver gene expression patterns, immune responses, and the progression of liver damage, including the development of liver malignancies. Factors such as obesity, alcohol consumption, and smoking, along with social determinants, may interact with hormone-related mechanisms of liver damage. The research provides a comprehensive review of gender-based differences in molecular mechanisms associated with liver carcinogenesis and the treatment of primary and metastatic liver tumors. [Extracted from the article] |
