Abstrakt: |
A recent study conducted at Tel Aviv University focused on ACKR1/DARC-associated neutropenia (ADAN) in pediatric patients in Israel, particularly those of African and Jewish Yemenite descent. The research found that 42.6% of the 115 patients evaluated were diagnosed with ADAN, with 59% having severe neutropenia. The study highlighted the importance of testing for ADAN in children with isolated neutropenia without severe infections, as homozygosity for the ACKR1/DARC gene may eliminate the need for further investigation or treatment in certain cases. [Extracted from the article] |