| Autor: |
Purnamasari, Dian Hadi, Hikmah, Zahrah, Endaryanto, Anang |
| Předmět: |
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| Zdroj: |
Journal of Medicinal & Chemical Sciences; Oct2024, Vol. 7 Issue 10, p1318-1326, 9p |
| Abstrakt: |
Allergic rhinitis significantly affects children's quality of life by causing persistent symptoms that interfere with daily activities and sleep, while also exacerbating related conditions such as asthma and sinusitis. This study aims to evaluate the correlation between skin prick test (SPT) induration size and the severity of allergic rhinitis in pediatric patients, using the Combined Symptom Medication Score (CSMS) as a measure of disease severity. A cross-sectional design was employed, involving 45 children aged 1-18 years with clinically confirmed allergic rhinitis due to house dust mites (HDM). Bivariate analysis revealed no significant correlation between SPT induration size and CSMS scores (r = 0.18, p = 0.121). However, multivariate analysis identified a weak positive correlation between disease severity and factors such as family history of atopy (r = 0.779, p = 0.006) and the presence of atopic comorbidities (r = 0.286, p = 0.007). These findings suggest that while SPT alone may not reliably predict disease severity, combining SPT results with patientspecific factors provides better insights. The study highlights the need for a multifactorial approach to assessing pediatric allergic rhinitis, integrating objective and subjective measures. Future research should focus on developing comprehensive scoring systems that incorporate clinical and biomarker data to enhance diagnostic accuracy and individualized treatment strategies. This holistic approach could improve outcomes and quality of life for pediatric patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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