Prevalence And Impact of Hyponatremia in Stroke Patients: Insights from A Tertiary Care Hospital, Gujarat, India.

Autor: Pandya, Nupur, Patel, Khushali L., Gandhi, Rina Viral, Solanki, Sunita
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Zdroj: European Journal of Cardiovascular Medicine; 2024, Vol. 14 Issue 4, p674-679, 6p
Abstrakt: Introduction: Stroke, a rapid onset cerebral deficit, is a leading cause of disability and mortality. Electrolyte imbalances, particularly hyponatremia, are common in stroke patients and linked to poor outcomes. Differentiating between conditions like SIADH and CSWS is crucial for effective treatment. This study aimed to evaluate serum sodium levels and investigates hyponatremia causes in newly diagnosed stroke patients. Materials & Methods: A total of 210 stroke patients were studied over six months using consecutive sampling. Patients over 18 years old admitted within 48 hours of stroke onset, diagnosed via CT or MRI, were included. Data, including demographics, clinical history, and laboratory measurements, were collected after informed consent. Various parameters including urinary sodium, serum osmolality, serum uric acid, serum sodium, urine specific gravity, blood glucose, blood urea, and blood urea nitrogen were measured. Results: Most stroke patients were aged between 56 and 75, with ischemic strokes being the most common (70.5%). A significant portion of patients had hyponatremia (40.0%), with SIADH being more prevalent (64.3%) than CSWS (35.7%). Mortality rate among hyponatremic patients (42.9%) was higher compared to those without hyponatremia (18.3%). However, there was no significant difference in mortality rate between SIADH (42.6%) and CSWS patients (43.3%, p=0.94). Conclusion: Maintaining electrolyte balance, especially sodium levels, upon patient arrival is crucial due to its potential adverse effects. Hyponatremia, common in stroke patients, can worsen consciousness levels and neurological symptoms, necessitating careful assessment of its severity for effective management. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index