| Autor: |
Goswami, Megha, M., Ananthi, Patel, Mayur K., Gujarathi, Amit P. |
| Předmět: |
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| Zdroj: |
European Journal of Cardiovascular Medicine; 2024, Vol. 14 Issue 4, p265-268, 4p |
| Abstrakt: |
Introduction: Hypertension is a prevalent and significant cause of mortality, contributing to 18% of deaths globally. The incidence of essential hypertension escalates with advancing age, and individuals exhibiting higher blood pressure in their youth face an elevated risk of subsequent hypertensive complications. Morphological and physiological alterations in the vasculature have been implicated in the development and persistence of hypertension. This condition elevates the risk of cerebral, cardiac, and renal events. The primary aim of this study was to measure the arterial stiffness index (SI) and reflection index (RI) in both hypertensive subjects and an age-matched control group of normotensive individuals. Methods: A cross-sectional study involving 200 subjects aged 30 to 60 years was conducted. Subjects were divided into four groups: Group 1 (control group of healthy individuals) and three hypertensive groups classified by the duration of their illness. Arterial stiffness was assessed using SI and RI, derived from digital volume pulse (DVP) recordings. DVP was measured using a finger pulse photoplethysmography device. The data were analyzed using analysis of variance (ANOVA), with statistical significance defined as P < 0.05 in relation to arterial stiffness indices and hypertension duration. Results: The study found a progressive increase in hypertension prevalence with advancing age and longer hypertension duration. Participants aged 40-49 years exhibited the highest prevalence across all groups. Group I, with normal blood pressure, showed the lowest RI (0.50 ± 0.08) and SI (6.12 ± 0.09). RI and SI increased significantly in Group II, further escalating in Group III. Group IV displayed a slight RI decrease but continued SI increase. ANOVA analysis revealed significant differences in RI and SI among the groups. Pearson correlation analysis showed strong positive correlations between both RI and SI values with the duration of hypertension. Conclusion: The study demonstrates a strong positive correlation between the two arterial stiffness indices, RI and SI, and the duration of hypertension. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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