Autor: |
Pushpajothi, R., Senbagaraman, R. Aravinda, Manjula, V., Mohanaprabha, G., chand mohan singh, Saravanasingh karan, Arthi, G., Subathra, M., Karthi, S., Kavitha, S., Suguna, M., Antony, S. Justus |
Předmět: |
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Zdroj: |
European Journal of Cardiovascular Medicine; 2024, Vol. 14 Issue 4, p224-227, 4p |
Abstrakt: |
Background: The current study was designed to evaluate the efficacy of Thasadeepakkini Chooranam. Five group of albino rats of either sex were selected. Group I served as control and received regular rat food and drinking water ad libitum. Group II, III and IV, V rats received phenylhydrazine 10 mg/kg for 8 days orally to induce anaemia in rats. Rats that developed anaemia with haemoglobin concentration lower than 13 g/dl were recruited for the study. Tween 20 a vehicle received by group II. Group III received standard haematinic drug Vitamin B12 (10 ml/kg). Group IV &V received Thasadeepakkini Chooranam (500 mg/kg-1000mg/kg) diluted in a vehicle tween 20. Haematinic activity of Thasadeepakkini Chooranam in Phenyl hydrazine induced Anaemia in Rat. Phenyl hydrazine caused significant decrease (P < 0.05) in Hb concentration, RBC count and haematocrit value in all rats indicating Anaemia. After the administration of test drug Thasadeepakkini Chooranam, the hematological parameters are significantly increased (P < 0.05). Thus the results obtained from this study reveal that the Siddha Formulation Thasadeepakkini choornam has hematinic activity. Therefore this formulation can be used as an alternative remedy for anemia. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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