First Use of AXL Targeting in Metastatic, Refractory, Adenoid Cystic Carcinoma: A Case Report.

Autor: Hoff, Camilla O., Dal Lago, Eduardo Andreazza, Siqueira, Juliana Mota, de Sousa, Luana G., El-Naggar, Adel K., Ahnert, Jordi Rodon, Ferrarotto, Renata
Předmět:
Zdroj: JCO Precision Oncology; 12/1/2024, Vol. 8, p1-7, 7p
Abstrakt: The article in JCO Precision Oncology discusses the first use of AXL targeting in metastatic, refractory adenoid cystic carcinoma (ACC) through a case report. The patient, a 28-year-old woman with ACC-II subtype, experienced significant clinical improvement and tumor regression after receiving AXL-targeted therapy (BA3011) as part of a phase I study. The study highlights the potential therapeutic implications of ACC subtypes and the promising response to AXL-targeted therapy in ACC, suggesting further investigation in this area. [Extracted from the article]
Databáze: Complementary Index