| Autor: |
Zhang, Qi, Wu, Shanghui, Wu, Xuesong |
| Předmět: |
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| Zdroj: |
Green Chemistry; 11/21/2024, Vol. 26 Issue 22, p11334-11339, 6p |
| Abstrakt: |
As enzyme mimics, metal porphyrin complex catalysts have become increasingly powerful for facilitating alkyl radical transformations. This report describes an iron porphyrin/photoredox catalytic manifold that enables the heteroselective assembly of sp3-hybridized carbon frameworks from diverse aliphatic carboxylic acids. The double decarboxylative cross-coupling reaction features mild and redox-neutral conditions, good functional group tolerance, and high heteroselectivity. Due to their opposing redox characteristics, photoredox-mediated electron shuttling between carboxylic acids and NHPI esters provides ready access to distinct alkyl radicals in the absence of external oxidants or reductants. The iron porphyrin-catalyzed radical-sorting SH2, evidenced by mechanistic studies, is proposed to be responsible for the highly selective radical–radical heterocoupling. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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