| Autor: |
Ma, Zhuang, Wu, Zechen, Kreyenschulte, Carsten, Bartling, Stephan, Lund, Henrik, Beller, Matthias, Jagadeesh, Rajenahally V. |
| Předmět: |
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| Zdroj: |
Green Chemistry; 11/21/2024, Vol. 26 Issue 22, p11140-11146, 7p |
| Abstrakt: |
A general cobalt-catalyzed α-alkylation of nitriles with alcohols is reported. Utilizing this straightforward borrowing hydrogen methodology, a series of substituted and functionalized nitriles can be easily coupled with benzylic, heterocyclic, and aliphatic alcohols to prepare diverse functionalized nitriles in good to excellent yields (>70 examples). Key for this synthesis is the use of specific cobalt-nanoparticles supported on N-doped carbon, which were conveniently prepared by pyrolysis of a templated material generated in situ by mixing cobalt chloride, zinc chloride, D -glucosamine hydrochloride, and colloidal silica, and subsequent removal of the silica. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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