| Abstrakt: |
Researchers from NOVA Southeastern University conducted a study on the adverse effects of systemic fluoride application on dentine formation in an experimental mouse model. The study found that excessive fluoride consumption can lead to dental fluorosis and impact dentine microstructure. Mice treated with high doses of fluoride showed enamel hypoplasia, dentine dysplasia, and external resorption of incisors. The research concluded that systemic fluoride application can cause structural, chemical, and mechanical changes in dentine, along with pulp inflammation. [Extracted from the article] |
