Reports Summarize Encephalitis Research from University of Oxford (Novel risk loci in LGI1-antibody encephalitis: genome-wide association study discovery and validation cohorts).

Předmět:
Zdroj: Genomics & Genetics Weekly; 11/15/2024, p1437-1437, 1p
Abstrakt: A recent study conducted at the University of Oxford focused on encephalitis with antibodies to leucine-rich glioma-inactivated 1 (LGI1-Ab-E), a form of autoimmune encephalitis. The research identified new genetic loci outside of the known major HLA signal, implicating PTPRD and LINC00670 genes. These findings offer potential markers for susceptibility, prognostics, and therapeutic responses in LGI1-Ab-E patients. [Extracted from the article]
Databáze: Complementary Index