MARINE NATURAL PRODUCTS AS ANTIVIRAL AGENTS: CURRENT ADVANCES AND FUTURE PERSPECTIVES.

Autor: Mohapatra, Rashmi, Jhankar, Jaiminee, Libin, V., Giri, Damayanti, Pal, Shweta Kailash, Sampath, V.
Předmět:
Zdroj: Biochemical & Cellular Archives; Oct2024, Vol. 24 Issue 2, p1435-1441, 7p
Abstrakt: Encompassing more than 70% of the Earth's surface, the ocean is an extensive and mostly unexplored repository of biodiversity, containing a remarkable variety of living organisms. Of these, marine species including algae, sponges, fungi, bacteria and invertebrates have attracted scientific attention because of their capacity to synthesize a diverse range of bioactive constituents. Recently, there has been considerable interest in marine natural products for their potential as innovative antiviral agents. The present review examines the latest progress in the identification and advancement of marine-derived chemicals exhibiting antiviral properties. We analyze the processes by which these chemicals exercise their effects, which include the suppression of viral entrance, replication and the adjustment of host immunological responses. In addition, we emphasize the role of these natural compounds in fighting new viral infections like SARS-CoV-2 and other respiratory viruses, as well as their possible application in treating neglected tropical diseases. Notwithstanding the encouraging outcomes, the advancement of antiviral drugs generated from marine sources encounters many obstacles, encompassing concerns pertaining to extraction, sustainability, and growth. Yet, progress in biotechnological methods, such as synthetic biology and nanotechnology, provide fresh possibilities to surmount these obstacles. The potential for the advancement of next-generation antiviral treatments may be found in marine natural compounds, suggesting a fruitful direction for the future of antiviral medication research. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index