| Autor: |
Hoang Anh T. Phan, Yanan Chang, Eaton, Samuel A., Petersson, E. James |
| Předmět: |
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| Zdroj: |
Chemical Communications; 11/18/2024, Vol. 60 Issue 89, p13075-13078, 4p |
| Abstrakt: |
Dipeptidyl peptidase 4 (DPP-4) is a promising biomarker for cancer and metabolic diseases. We demonstrate the design of novel fluorescent DPP-4 probes based on the protease's native substrates using a thioamide as a quencher for measuring in vitro kinetics, inhibition with sitagliptin, and DPP-4 activity in saliva samples. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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