Editorial: Structure and function of the immunological and redirecting artificial synapses and their clinical implications.

Autor: Izquierdo, Manuel, Ruiz-Navarro, Javier, Baldari, Cosima T., Roda-Navarro, Pedro
Předmět:
Zdroj: Frontiers in Immunology; 2024, p1-4, 4p
Abstrakt: The editorial discusses the structure and function of immunological and redirecting artificial synapses and their clinical implications. It highlights the importance of the immunological synapse (IS) in facilitating intercellular communication for efficient T and B lymphocyte activation. The article also explores the role of microvilli in antigen sensing and effector functions, as well as the implications of tumor cell reorganization at the IS. Additionally, it delves into T cell redirecting strategies for cancer immunotherapy and the challenges associated with CAR-T therapy. [Extracted from the article]
Databáze: Complementary Index