| Autor: |
Tracy, Evan Paul, Adereti, Iyanujesu, Chu, Justin, Brown, Julianna |
| Zdroj: |
BMJ Case Reports; Oct2024, Vol. 17 Issue 10, p1-8, 8p |
| Abstrakt: |
Hereditary haemorrhagic telangiectasia (HHT) leads to arteriovenous malformations (AVM) that increase the risk of haemorrhage and cause right-left shunting bypassing the reticuloendothelial system increasing the risk for recurrent infections. A 60+ year old male patient with HHT type 1 (status post six pulmonary AVM coiled embolisations) with epistaxis presented with intractable back pain, methicillin-sensitive Staphylococcus aureus (MSSA) bacteraemia and spinal MRI revealing spondylodiskitis and L4-L5 epidural phlegmon. He has an extensive history of deep-seated infections including two prior spinal infections, two joint infections and one muscular abscess—all with MSSA. The patient was treated with 6weeks of intravenous nafcillin with symptom resolution. Infectious disease prescribed cefalexin 500mg daily for suppression of infection recurrence considering his extensive deep-seated infection history and multiple risk factors. This case raises important questions about preventative antimicrobial management of high-risk patients with HHT, which is a grey area in current international HHT guidelines. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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