| Autor: |
Truong Giang, Dinh Thi, Trung, Hieu Tran, Tuan, Nguyen Hoang, Ha, Nguyen Xuan, Nguyen, Dang Khoa, Nguyen, Minh Chanh, Thu Hien, Nguyen Thi, Thuan, Vi Thi, Thu Hang, Tran Thi, Tra Giang, Ngu Thi, Van Trung, Hoang |
| Předmět: |
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| Zdroj: |
Journal of Essential Oil-Bearing Plants; Oct2024, Vol. 27 Issue 5, p1439-1448, 10p |
| Abstrakt: |
This work aimed to determine the chemical composition and antioxidant activity of rhizome essential oil (EO) of Meistera verrucosa growing wild in Ha Giang Province, Vietnam. The EO was isolated using hydrodistillation, then the chemical composition was analyzed by Gas chromatography-mass spectroscopy (GC-MS). In addition, the antioxidant activities were determined by the DPPH scavenging method and ferric reducing antioxidant power (FRAP) assay. The results showed that α-pinene, β-pinene, and (E)-β-ocimene were major components in the EO, accounting for 39.6%, 20.7%, and 12.2%, respectively. The EO showed antioxidant activity, the IC50 value of DPPH scavenging activity, and the EC50 value of FRAP assay were 91.01 mg/mL and 17.50 mg/mL, respectively. Furthermore, to evaluate the inhibitory interaction potential of Keap1, docking analysis indicated that α-pinene has the strongest affinity among the major compounds surveyed. The key interactions observed in the complexes of the major compounds with Keap1 are predominantly hydrophobic interactions (pi-sigma and pi-alkyl), which significantly contribute to their binding affinities. These results provide more information on the volatile compounds of the EO from the rhizomes of M. verrucosa and first reveal its antioxidant power. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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