| Autor: |
El-Nashar, Heba A. S., Abbas, Ahmad M., Al-Qaaneh, Ayman M., Abdel-Maksoud, Mostafa A., El-Tayeb, Mohamed A., Almutairi, Saeedah, Hafeez Kiani, Bushra, Elhawary, Esraa A. |
| Předmět: |
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| Zdroj: |
Journal of Essential Oil-Bearing Plants; Oct2024, Vol. 27 Issue 5, p1428-1438, 11p |
| Abstrakt: |
Montanoa bipinnatifida is a perennial shrub belonging to family Asteraceae and geographically distributed in Mexico, Central America and Northern South America. This study aimed to investigate the chemical composition of the essential oil isolated from M. bipinnatifida leaves through GC-MS analysis accompanied by in-depth investigation of antimicrobial properties against wide arrays of microbial strains via agar diffusion method and disk diffusion method. The GC-MS analysis of the tested oil revealed presence of sixteen components (∼99.99%), predominated by germacrene D (37.22%), β-caryophyllene (30.73%), α-pinene (4.56%) and β-germacrene (4.48%). The undiluted oil exhibits varying levels of activity against different microbes. The leaf oil showed a significant inhibition against Proteus mirabilis, Staphylococcus aureus, Bacillus subtilis (both vegetative and spores), Mycobacterium phlei, and Candida albicans. However, its activity against Sarcina lutea, Escherichia coli, Klebsiella pneumoniae appears to be less pronounced. Thus, the leaf oil of M. bipinnatifida demonstrates broadspectrum antimicrobial activity and is recommended in the pharmaceutical industry to overcome the current problem related to the microbial resistance to antibiotics. Further experimental studies are warranted to investigate the underlying mechanism of action and the responsible individual components. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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