Exploring the Therapeutic Potential of Selenium Nanoparticles in Central Nervous System Disorders: A Nanomedicine Approach.

Autor: Balaraju, Prajwal Chamanahalli, Manchegowda, Jayanth Baburayanakoppal, Kumar, Chandan, Raghunathanaidu, Bharathi Doddla, Doddi Hanumaiah, Ananth Gowda K M, Lokesha, Varun Nagamangala, Ahmed, Syed Sagheer
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Zdroj: International Journal of Pharmaceutical Investigation; Oct-Dec2024, Vol. 14 Issue 4, p1025-1034, 10p
Abstrakt: In the realm of healthcare, Central Nervous System disorders pose a formidable challenge, affecting countless lives globally. Conditions like Alzheimer's, Parkinson's and traumatic brain injuries exact a heavy toll. However, a glimmer of hope arises from the world of nanotechnology in the shape of Selenium Nanoparticles. Selenium, a trace element, is known for its antioxidant properties, but Selenium Nanoparticles take it a step further, offering enhanced antioxidant capabilities, better absorption and the ability to deliver therapeutic agents precisely where they're needed in the brain. Oxidative stress, a major player in many Central Nervous System disorders, faces a formidable adversary in Selenium Nanoparticles, potentially offering relief to those grappling with conditions characterized by oxidative damage. Selenium Nanoparticles also exhibit anti-inflammatory prowess, valuable for tackling neuroinflammation, a common feature in these disorders. Moreover, Selenium Nanoparticles pave the way for precision drug delivery within the brain, minimizing side effects while maximizing treatment efficiency. In summary, Selenium Nanoparticles represent a promising frontier in the ongoing battle against Central Nervous System disorders, offering a glimpse of innovative solutions that could alleviate the burdens of these complex neurological conditions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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