DXA-derived abdominal fat-free mass to predict MRI skeletal muscle mass in postmenopausal women.

Autor: Walker, E., Chalke, A.M., Bland, V.L., Lind, K.E., Chen, Z., Blew, R.M., Odegaard, A.O., Thomson, C.A., Caan, B., Nicholas, J.S., Valencia, C.I., Roe, D.J., Allison, M., Schnatz, P.F, Wactawski-Wende, J., Bea, J.W.
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Zdroj: Applied Physiology, Nutrition & Metabolism; 2024, Vol. 49 Issue 11, p1606-1610, 5p
Abstrakt: Dual-energy X-ray absorptiometry (DXA) is more available than gold-standard magnetic resonance imaging (MRI), but DXA ability to estimate abdominal skeletal muscle mass (SMM) is unknown. DXA-derived abdominal fat-free mass (FFM; Hologic QDR2000 or QDR4500w) was correlated with single-slice MRI SMM at L4 (N = 69; r QDR2000 = 0.71, QDR4500w = 0.69; p < 0.0001). Linear regression to predict SMM, including DXA FFM, BMI, and age, resulted in an R-squared of 0.72 and 0.65 for QDR2000 and QDR4500. Bland-Altman limits of agreement were ±21 and ±31 g for 2–3 standard deviations from the mean difference. DXA predicted abdominal SSM is a moderate proxy for MRI abdominal SMM. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index