| Autor: |
Tran, Phuong Ha, Vu, Thi Thanh Tam, Phan, Thi Diem Tran, Nguyen, Van Mien, Ngo, Thi Nghia Minh, Le, Canh Viet Cuong, Ton, That Huu Dat |
| Předmět: |
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| Zdroj: |
World Academy of Sciences Journal; Nov/Dec2024, Vol. 6 Issue 6, pN.PAG-N.PAG, 1p |
| Abstrakt: |
The genus Melaleuca (Myrtaceae) is a valuable plant resource for research and applications in medicine, pharmacy, the pharmaceutical industry and folklore medicine. The present study aimed to investigate the chemical components and biological properties of the essential oils (EOs) of three Melaleuca species. Gas chromatography-mass spectrometry analyses revealed that the EOs extracted from the leaves of M. cajuputi, M. quinquenervia and M. leucadendra contained 19-21 compounds with high amounts of oxygenated monoterpenes and sesquiterpenes. Subsequent bioassays demonstrated that the EOs of M. cajuputi, M. quinquenervia and M. leucadendra exhibited antimicrobial activity against all tested microorganisms, including Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aegurinosa and Candida albicans, with minimum inhibitory concentrations in the range 640-2,560 µg/ml. The same EOs exerted inhibitory effects against α-amylase, α-glucosidase, acetylcholinesterase and xanthine oxidase with IC50 values ranging from 331.9±20.64 to 1,453±93.79 µg/ml. The findings obtained in the present study provide additional insight into the enzyme inhibitory properties of the leaf EOs from Melaleuca species that have not been reported in previous research, at least to the best of our knowledge. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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