New Prostate Cancer Study Results Reported from Memorial Sloan-Kettering Cancer Center (The Neuroendocrine Transition In Prostate Cancer Is Dynamic and Dependent On Ascl1).

Předmět:	ANDROGEN receptors NEWSPAPER editors CANCER invasiveness ELECTRONIC records TRANSCRIPTOMES PROSTATE cancer
Zdroj:	Clinical Oncology Week; 11/5/2024, p794-794, 1p
Abstrakt:	A recent study conducted at Memorial Sloan-Kettering Cancer Center in New York City explored the neuroendocrine transition in prostate cancer, focusing on lineage plasticity and therapy outcomes. The research introduced an in vivo platform to investigate the transformation of neuroendocrine lineage throughout prostate cancer progression. Findings revealed that the depletion of Ascl1 blocks plasticity and leads to cancer that is sensitive to castration, highlighting the importance of therapy timing in addressing prostate cancer. This research offers valuable insights into the dynamics and key factors of neuroendocrine lineage transformation in prostate cancer. [Extracted from the article]
Databáze:	Complementary Index
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