New Findings from Nanjing University of Chinese Medicine in the Area of Cardiomyopathies Reported (Salvianolic Acid B Inhibits Myocardial Fibrosis During Diabetic Cardiomyopathy Via Suppressing Trpc6 and Tgf-b/smad3 Pathway).

Předmět:	TRANSFORMING growth factors TRP channels CARDIAC hypertrophy SIGNAL peptides HEART diseases
Zdroj:	Cardiovascular Week; 11/4/2024, p671-671, 1p
Abstrakt:	Researchers from Nanjing University of Chinese Medicine have found that Salvianolic acid B (Sal B) inhibits myocardial fibrosis during diabetic cardiomyopathy by suppressing the TRPC6 and TGF-b/Smad3 pathway. This study, supported by the National Natural Science Foundation of China, used diabetic mouse models and in vitro cell models to demonstrate the beneficial effects of Sal B in mitigating myocardial fibrosis. The research concludes that Sal B alleviates myocardial fibrosis in diabetes by modulating TRPC6 expression and the TGF-b/Smad3 signaling pathway. [Extracted from the article]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu