Abstrakt: |
A study conducted at Thayer School of Engineering at Dartmouth focused on measuring intracellular oxygen levels during ultra-high dose rate radiation therapy. The research used protoporphyrin IX (PpIX) delayed fluorescence as an intracellular oxygen sensor and compared it to extracellular oxygen levels. The study found a direct correlation between intracellular and extracellular oxygen changes during radiation therapy, suggesting a potential new approach to measuring intracellular oxygen depletion in living tissue. This research, which has been peer-reviewed, could have implications for estimating intracellular reactive oxygen species production. [Extracted from the article] |