| Autor: |
Drabent, P., Kervarrec, T., Tallet, A., Fraitag, S. |
| Zdroj: |
Virchows Archiv: European Journal of Pathology; Oct2024, Vol. 485 Issue 4, p729-733, 5p |
| Abstrakt: |
The article discusses a new entity called neonatal spindle-cell CD34-positive plaque-like tumour, characterized by NTRK gene fusion. The study conducted on 11 cases found that these tumours were mostly congenital or arose in the first month of life, with a benign clinical course. The tumours showed a distinct histological pattern and a common LMNA::NTRK1 fusion transcript, suggesting they may represent a unique subgroup of tumours among NTRK-rearranged spindle cell neoplasms. Further research is needed to determine the exact classification of these tumours within the spectrum of paediatric NTRK-rearranged spindle cell neoplasms. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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