Вплив хронічного стресу на гормональний стан жінок, які постраждали від бойових дій, та жінок-переселенок.
| Autor: | Подольський, Вол. В., Подольський, В. В., Медведовська, Н. В., Емір-Усеінова, Д. А., Боцюк, У. І. |
|---|---|
| Předmět: |
PROGESTERONE
SEX hormones REPRODUCTIVE health MENTAL health PITUITARY gland PSYCHOLOGY of women WAR EMOTIONS HYDROCORTISONE IMMUNOENZYME technique OLIGOMENORRHEA ESTRADIOL PROLACTIN PSYCHOLOGICAL stress FOLLICLE-stimulating hormone LUTEINIZING hormone MENSTRUAL cycle HYPOTHALAMIC-pituitary-adrenal axis REFUGEES AMENORRHEA |
| Zdroj: | Reproductive Health of Woman; 2024, Vol. 72 Issue 6, p8-13, 6p |
| Abstrakt: | The objective: to assess the impact of chronic stress caused by war and displacement on the hormonal balance of refugee women. Materials and methods. 60 women were examined, who were divided into groups: the 1st group included women who were affected by hostilities (20 persons), and the 2nd group included displaced women (20 individuals). In these 40 women the hormonal studies were conducted in the conditions of military aggression in Ukraine. The control group (3rd group) included healthy women who were examined in the pre-war period. All examined women were 20–25 years old with an average body weight of 55–60 kg. Concentrations of progesterone, estradiol, follicle-stimulating hormone (FSH) and luteinizing hormone, prolactin in the I and II phases of the menstrual cycle (MC), cortisol in the I phase of the MC were determined in blood serum using the enzyme immunoassay method. An analysis of the results of research on the role of the hypothalamic-pituitary-adrenal system in the regulation of the stress response was carried out. Results. In the examined women, various disorders of MC were observed, such as: menometrorrhagia, hypermenorrhea, acyclic uterine bleeding, oligomenorrhea, and amenorrhea. The most pronounced changes in menstrual function were observed in women who were affected by hostilities. Such significant disorders of MC in women of this group coincided with changes in indicators of gonadotropic hormones of the pituitary gland and sex hormones in the blood. A study of the psycho-emotional state of women who suffered from hostilities established that these women have a significant stressful effect of various risk factors on the body. Changes in the levels of cortisol, prolactin and other hormones were detected. Conclusions. Studies have shown that chronic stress affects the hormonal status of women affected by hostilities and of displaced women, including FSH, estradiol, and prolactin levels. A significant increase in the level of FSH in the follicular phase of the menstrual cycle and an increase in the level of estradiol in the luteal phase were determined, which may indicate a compensatory reaction of the body to stress. A significant increase in the level of prolactin was also found, which can cause disorders of menstrual function and affect the psycho-emotional state. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
| Externí odkaz: |
|