| Autor: |
Biała, Martyna, Babicki, Mateusz, Malchrzak, Wojciech, Janiak, Sandra, Gajowiak, Dominik, Żak, Alan, Kłoda, Karolina, Gibas, Piotr, Ledwoch, Justyna, Myśliwiec, Anna, Kopyt, Daria, Węgrzyn, Anna, Knysz, Brygida, Leśnik, Patrycja |
| Předmět: |
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| Zdroj: |
Pathogens; Oct2024, Vol. 13 Issue 10, p846, 10p |
| Abstrakt: |
Streptococcus pyogenes is responsible for 20–30% of pharyngitis in children and 5–15% in adults. The ineffective treatment of group A Streptococcus (GAS) infections can result in postinfectious sequelae. This study aims to evaluate the frequency of GAS pharyngitis and assess the management of patients with pharyngitis and antibiotic use. We conducted a multicenter, retrospective analysis of medical records from nine primary care centers in Poland. The study enrolled 1949 medical records of patients (children 67.4%, adults 32.6%). An infection of Streptococcus pyogenes, based on a rapid strep test, was diagnosed in 830 patients (42.6%). In the comprehensive study group of 1949 patients, 1054 (54.1%) were given antibiotics. Notably, 224 patients had a negative rapid strep test result but still received antibiotic treatment, underscoring the complexity of treatment decisions. The most commonly used antibiotics were oral penicillin V in 431 cases (41%) and amoxicillin in 219 cases (20.8%). We observed no significant difference between positive rapid strep test results and patients' sociodemographic data and comorbidities. The prevalence of GAS was 42.6% in the analyzed records of patients with pharyngitis, and 54.1% were prescribed antibiotics. Antibiotics were overprescribed for sore throats. Strategies are needed to promote rational antibiotic use. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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