| Autor: |
El Hennawy, Hany M., Safar, Omar, Al Faifi, Abdullah S., Shalkamy, Osama, El Madawie, Mahmoud Z., Thamer, Saad, Almurayyi, Muath, Alqarni, Abdullah Mohammed, Amri, Sami Saleh, Hawan, Ali Abdullah, Elatreisy, Adel |
| Předmět: |
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| Zdroj: |
Archives of Italian Urology & Andrology / Archivio Italiano di Urologia Andrologia; Sep2024, Vol. 96 Issue 3, p1-5, 5p |
| Abstrakt: |
Background: Erectile dysfunction (ED) and sex hormone profile disturbances are common in ESRD patients. Objective: To assess the effect of kidney transplant (KT) and Hemodialysis/peritoneal dialysis (HD/PD) on the serum sex hormone profile and sexual functions in ESRD patients with ED. Patients and methods: A single-center, non-concurrent cohort study included a hundred ESRD patients with ED, on regular HD/PD (group A, n = 50) and after KT (group B, n = 50) at Armed Forces Hospitals Southern Region, KSA. Results: the mean age of patients was 47.3 ± 7.01 and 56.8 ± 9.6 years in groups A and B, respectively. The cohorts were comparable regarding patient demographics, apart from a higher incidence of comorbidities in group B. After KT the mean testosterone level was higher in Group B (13.64 ± 3.21 nmol/L Vs 10.26 ± 3.26 nmol/L, p < 0.001). Similarly, LH and prolactin levels were lower in group B than in group A (p < 0.05). As regards sexual function, ED was reported in 92% of patients in group A compared to 42% in group B (p < 0.001). In groups A and B, mild ED was found in 48% and 14% of patients, while moderate ED was found in 16% and 8%, respectively. The mean total IIEF-15 score was 36.42 ± 9.33 and 43.87 ± 9.146 in groups A and B, respectively (p = 0.0001). Sexual desire and orgasm were significantly better in Group B. Conclusions: Our study showed that kidney transplantation could improve erectile function and restore normal sex hormone levels in ESRD male patients with ED, with better outcomes compared to HD/PD. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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