| Autor: |
Nagaki, Jun, Kawasaki-Takasuka, Tomoko, Mori, Keiji |
| Předmět: |
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| Zdroj: |
Synlett; Nov2024, Vol. 35 Issue 18, p2143-2147, 5p |
| Abstrakt: |
We report a unique synthetic route to benzo[7]annulene derivatives. When benzylidene malonates having a 1-(N , N -dialkylamino)alkyl group at the ortho -position are treated with a stoichiometric amount of M(OTf)3 (M = Sc, Yb, Gd), three transformations ([1,4]-hydride shift/isomerization into an enamine/intramolecular Stork enamine acylation) proceed sequentially to afford various benzo[7]annulene derivatives in moderate chemical yields. To our knowledge, the present reaction is the first example of an internal redox reaction involving a [1, n ]-hydride shift/(n +3)-cyclization process. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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